Highly accomplished Bioengineering PhD with extensive expertise in AI/ML, model-based optimization, and bioinformatics, driving innovation from theoretical research to commercial products. Leverages a comprehensive background spanning mathematics, physics, and clinical medicine to develop high-impact solutions, particularly in medical diagnostics, drug discovery, and industrial safety. Proven leader in interdisciplinary projects, adept at translating complex scientific concepts into tangible, quantifiable outcomes and intellectual property.
Hong Kong, Hong Kong, Hong Kong
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Summary
Leads multi-omics integrative analysis and AI product development for personalized cancer treatment and clinical decision support systems.
Highlights
Developed a multi-omics integrative analysis system for classifying radiotherapy sensitivity in nasopharyngeal carcinoma (NPC) and aiding personalized treatment.
Established and applied mathematical models and software to address clinical diagnosis and treatment challenges, validating models with q-PCR on hospital clinical samples.
Secured funding and managed research projects (TCFS/HMRF), overseeing research group operations and providing guidance to PhD students.
Spearheaded the HMRF project as Principal Investigator, developing an AI product that achieves high performance with limited samples, protects privacy, and provides interpretable reasoning for medical knowledge.
Advisor
Shenzhen, Guangdong, China
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Summary
Provided expert technical support and bioinformatics analysis for drug research and development, guiding strategic R&D initiatives for long-non-coding gene targeted drugs.
Highlights
Delivered critical technical support for experimental drug research and development plans, enhancing project execution and data integrity.
Guided bioinformatics analysis, ensuring robust data interpretation for Huayuan Biotechnology's R&D efforts.
Offered strategic recommendations on the company's research and development direction, influencing key biotechnological decisions.
Collaborative Researcher
Shanghai, Shanghai, China
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Summary
Conducted professional data analysis for bulk-sequencing to support the development of novel CAR-T therapy products for a Fortune Global 500 company.
Highlights
Performed professional data analysis for bulk-sequencing with small data sizes, supporting the advancement of new CAR-T therapy products.
Contributed to a Fortune Global 500 company's strategic initiatives in developing cutting-edge biotechnological solutions.
Ensured data integrity and analytical rigor, directly impacting the development pipeline for CAR-T therapies.
Technical Director
Beijing, Beijing, China
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Summary
Led product development and strategic initiatives for an AI-powered gas pipeline leak detection and analysis system, leveraging patented technology to achieve world-leading accuracy.
Highlights
Directed the development of an AI analysis system and intelligent monitoring station for underground gas pipe leaks, leveraging proprietary academic achievements.
Implemented patented technology to create the world's most accurate gas pipeline leak detection and analysis system, achieving cm-level locating results within seconds.
Participated in strategic development decisions and oversaw international collaborations, driving business growth and market expansion.
Secured 100% domestically produced software and hardware with complete independent intellectual property rights, enhancing market competitiveness.
Edinburgh, Scotland, UK
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Summary
Instructed Mechanical Engineering Design 2B, focusing on MATLAB programming and mechanical design principles, enhancing student understanding and practical skills.
Highlights
Delivered instruction in MATLAB programming and core mechanical design and optimization principles to engineering students.
Assessed student work, providing feedback to enhance understanding and application of complex engineering concepts.
Contributed to the academic development of future engineers through practical demonstrations and theoretical guidance.
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Doctor of Philosophy (PhD)
Bioengineering
Courses
Optimisation of Microfluidic Experiments
Model Calibration of Synthetic Promoters
Automated Microfluidic Experiments for Model Calibration
Model-Based Optimal Experimental Design with Parameter Clustering
Automatic Experiment Abnormality Screening based on Convolutional Neural Network
Awarded By
University of Manchester
Awarded for exceptional academic performance in MSc of Mechanical Engineering Design.
Published by
Nature Communications
Summary
Investigated and visualized bioinformatics data, with methods applicable to other diseases and mechanisms, advancing understanding of cancer metastasis.
Published by
Clinical and Translational Medicine
Summary
Developed a new Pareto-optimization solution for multi-centre study, applicable to other diseases, contributing to understanding metastasis risk factors.
Published by
China National Copyright Administration
Summary
Registered China Software Copyright No. 2025SR1952903 for the AIUPL System.
Published by
US Patent Office
Summary
Filed US patent application No.63/595,157 (PCT/CN2024/128778) for a method undergoing commercialization by HKU.
Published by
China National Copyright Administration
Summary
Registered China Software Copyright No. 2023SR078901 for Pipeline Leak Fast Detection Software.
Published by
China National Intellectual Property Administration
Summary
Secured China Patent No. 202311091637.1 for a leak detection system, leading to commercial products.
Published by
China National Intellectual Property Administration
Summary
Secured China Patent No. 202210626622.X for a sampling layout method, leading to commercial products.
Published by
Processes
Summary
Improved algorithm for optimal experimental design, particularly for experimental designs for models with multiple parameters.
Published by
Journal of Natural Gas Science and Engineering
Summary
Successfully applied first-principle modelling, leading to the world's most accurate leakage locating product in the market 4 years later.
Published by
China National Intellectual Property Administration
Summary
Co-inventor of China Patent No.201710465110.9, awarded the High-Tech Entrepreneurship Grant in Hangzhou.
Published by
China National Intellectual Property Administration
Summary
Secured China Patent No. 201610007922.4, with relevant concepts now widely known as “AI agents”.
Native
Fluent
Basic
R, Python, C#, C++, JAVA, Arduino, Processing, MATLAB.
R Studio, MATLAB, Sketchpad, Mathematica, MathCAD, LabVIEW, SPSS, Visual Studio, Balsamiq Wireframes, Mockplus, MIT App Inventor, Auto CAD, SolidWorks, ABAQUS, 3D Builder, 3ds Max, Photoshop CC, Apowersoft, LaTeX.
Biochemical Lab (P1 & P2), Sterile Operation (Class I/II laminar flow hoods), Microfluidics (design, manufacture, use), Digital Fluorescent Microscope (automated control, operation, data process), OD Measurement, Plate Reader, Q-PCR, Incubator, Laboratory Oven, Vacuum Autoclave, Oxygen Plasma Cleaner, Ultrasonic Cleaner, Lab Safety Management.
Team Leadership, Project Coordination, Schedule Management, International Trade Cooperation Negotiation, Remote Working, Strategic Planning, Research & Development Management, Intellectual Property Management, Grant Writing, Mentorship.
Model-Based Optimization, Bioinformatics Analysis, Multi-omics Integrative Analysis, Generative Adversarial Networks (GAN), Optimal Experimental Design (OED), Convolutional Neural Networks (CNN), Statistical Analysis, AI Modeling, Algorithm Design, Image-Based Abnormality Screening, Data Synthesis/Enrichment, Predictive Modeling.
Mechanical Design, IoT, 3D Printing, Quantum Networks, Microfluidic Systems, First-Principle Modelling, Multi-Discipline Optimization.
American Association for Cancer Research (since 2025), Hong Kong Research Talent Hub for Innovation and Technology Fund projects (since 2022), International Doctorate Association (since 2022), IEEE Peer Reviewer (2023), ACS Peer Reviewer (2022).
Electronic Keyboard, Piano, Guqin, Hulusi, Bawu, Cello, Tin Whistle.
Fencing, Taekwondo.
High-order Rubik's Cubes, Bartending (hand-brewed coffee and cocktail mixing), Origami.
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Summary
Led a 4-person team at the University of Manchester to design and build an electro-mechanical window blind system with integrated IoT capabilities, from initial concept to physical prototype within 3 months.
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Summary
Participated as a researcher in a project sponsored by Beijing Municipal Commission and Beijing Gas Refco Group Ltd. to develop a multivariable real-time online intelligent safety precaution and analysis system for natural gas regulators.